Across TCGA patient cohorts, ADH7 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ADH7-associated genes across cancer lineages are p90 RSK, PRAS40_pT246, and Tuberin_pT1462. Each is linked with ADH7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADH7-to-partner and partner-to-ADH7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADH7→partner) and Y-score (partner→ADH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	p90 RSK →	+0.199	+2.000	.034	.031	3	2
UCEC	PRAS40_pT246 →	+0.187	+2.183	.037	.035	3	1
UCEC	Tuberin_pT1462 →	+0.413	+2.999	<.001	.035	3	1
UCEC	Chk2 →	-0.267	-3.321	.029	.010	3	1
SKCM	Acetyl-a-Tubulin-Lys40 →	+0.736	+2.700	.002	.006	3	1
SKCM	Ku80 →	+0.289	+3.000	.019	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

ADH7 survival (RNA) · tumor vs normal (RNA) · all ADH7 data types