ADH6

Across TCGA cell cohorts, ADH6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,183 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADH6-associated GO terms across cancer lineages are Regulation of cytoplasmic translational initiation, Regulation of mRNA splicing, via spliceosome, and Transcription elongation-coupled chromatin remodeling. Each is linked with ADH6 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADH6-to-partner and partner-to-ADH6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytoplasmic translational initiation grouped by ADH6-low versus ADH6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADH6→partner) and Y-score (partner→ADH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cytoplasmic translational initiation →	+0.103	+0.269	<.001	.003	3	6
BLOOD_Lymphoma	Regulation of mRNA splicing, via spliceosome →	+0.075	+0.128	<.001	<.001	3	6
BONE	Transcription elongation-coupled chromatin remodeling →	+0.095	+0.336	.008	<.001	3	6
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.088	+0.136	<.001	<.001	3	6
SKIN	Negative regulation of chromosome condensation →	+0.113	+0.187	<.001	.001	2	7
BLOOD_Lymphoma	Regulation of RNA splicing →	+0.065	+0.127	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,183 associations by consensus.

Regulation of cytoplasmic translational initiation by ADH6 expression — BONE

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