Across TCGA patient cohorts, ADH4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,461 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ADH4-associated proteins across cancer lineages are ADH5, SEPTIN4, and ADD3. Each is linked with ADH4 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADH4-to-partner and partner-to-ADH4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADH4→partner) and Y-score (partner→ADH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ADH5 →	+0.357	+0.669	<.001	.006	3	5
OV	SEPTIN4 →	+0.671	+0.601	<.001	<.001	3	4
LUAD	ADD3 →	+0.350	+0.696	<.001	<.001	3	4
OV	FBLIM1 →	+0.799	+0.665	<.001	.005	3	4
PDAC	HOPX →	+0.603	+0.550	.001	.004	2	5
LUAD	HSP90AB1_S226 →	-0.387	-0.364	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,461 associations by consensus.

Exploration

ADH4 survival (RNA) · tumor vs normal (RNA) · all ADH4 data types