Across TCGA cell cohorts, ADH4 RNA expression is significantly associated with the go_rna of many other GO terms, with 391 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible ADH4-associated GO terms across cancer lineages are Regulation of calcium ion export across plasma membrane, Regulation of adenylate cyclase activity, and Positive regulation of response to endoplasmic reticulum stress. Each is linked with ADH4 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADH4-to-partner and partner-to-ADH4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADH4→partner) and Y-score (partner→ADH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of calcium ion export across plasma membrane →	+0.084	+0.029	<.001	.006	2	4
BREAST	Regulation of adenylate cyclase activity →	-0.126	-0.044	<.001	.002	3	3
BREAST	Positive regulation of response to endoplasmic reticulum stress →	+0.041	+0.042	.009	.003	3	3
BLOOD_Leukemia	Negative regulation of stem cell differentiation →	+0.080	+0.015	.001	.004	3	3
LIVER	Carboxylic acid catabolic process →	+0.076	+2.063	<.001	.004	3	3
LIVER	Cellular response to toxic substance →	+0.120	+1.384	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 391 associations by consensus.

Exploration

ADH4 survival (RNA) · tumor vs normal (RNA) · all ADH4 data types