ADH1C

Across TCGA cell cohorts, ADH1C RNA expression is significantly associated with the go_rna of many other GO terms, with 1,141 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ADH1C-associated GO terms across cancer lineages are Tricarboxylic acid cycle, Positive regulation of iron ion transport, and Positive regulation of iron ion transmembrane transport. Each is linked with ADH1C in more than 6 cancer types. Because this analysis shows association rather than direction, both ADH1C-to-partner and partner-to-ADH1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tricarboxylic acid cycle grouped by ADH1C-low versus ADH1C-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADH1C→partner) and Y-score (partner→ADH1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Tricarboxylic acid cycle →	+0.081	+1.009	<.001	.009	2	7
BLOOD_Leukemia	Positive regulation of iron ion transport →	+0.739	+0.133	<.001	<.001	3	6
BLOOD_Leukemia	Positive regulation of iron ion transmembrane transport →	+0.739	+0.133	<.001	<.001	3	6
STOMACH	Terpenoid catabolic process →	+1.041	+2.099	<.001	.002	3	5
KIDNEY	Susceptibility to natural killer cell mediated cytotoxicity →	-0.214	-0.374	.003	.004	3	5
BLOOD_Lymphoma	Regulation of cartilage development →	-0.073	-0.051	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,141 associations by consensus.

Tricarboxylic acid cycle by ADH1C expression — BREAST

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