ADGRL4

Across TCGA cell cohorts, ADGRL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 952 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ADGRL4-associated GO terms across cancer lineages are Establishment of protein localization to vacuole, Protein localization to membrane, and Positive regulation of response to endoplasmic reticulum stress. Each is linked with ADGRL4 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADGRL4-to-partner and partner-to-ADGRL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to vacuole grouped by ADGRL4-low versus ADGRL4-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRL4→partner) and Y-score (partner→ADGRL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Establishment of protein localization to vacuole →	+0.050	+0.121	.004	.004	3	6
BONE	Protein localization to membrane →	+0.088	+1.584	<.001	.007	3	5
PANCREAS	Positive regulation of response to endoplasmic reticulum stress →	+0.043	+0.105	.005	.006	3	5
BONE	Positive regulation of focal adhesion assembly →	+0.163	+1.771	.002	.008	3	5
SOFT_TISSUE	Regulation of interleukin-6-mediated signaling pathway →	+0.115	+0.981	<.001	.009	3	5
BONE	Negative regulation of dendritic cell antigen processing and presentation →	+1.430	+1.783	<.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 952 associations by consensus.

Establishment of protein localization to vacuole by ADGRL4 expression — PANCREAS

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