ADGRL2

Across TCGA cell cohorts, ADGRL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,777 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADGRL2-associated GO terms across cancer lineages are Cardiac muscle cell action potential involved in contraction, Response to water, and Regulation of ERAD pathway. Each is linked with ADGRL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADGRL2-to-partner and partner-to-ADGRL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiac muscle cell action potential involved in contraction grouped by ADGRL2-low versus ADGRL2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRL2→partner) and Y-score (partner→ADGRL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cardiac muscle cell action potential involved in contraction →	-0.201	-2.713	.008	.008	3	7
LUNG_NSCLC_LUSC	Response to water →	+0.174	+2.348	.002	.008	3	7
STOMACH	Regulation of ERAD pathway →	+0.081	+2.645	<.001	<.001	3	7
STOMACH	Regulation of protein localization to Cajal body →	+0.104	+3.106	<.001	.001	3	7
STOMACH	Positive regulation of protein localization to Cajal body →	+0.104	+3.106	<.001	.001	3	7
OESOPHAGUS	Positive regulation of viral genome replication →	+0.125	+2.480	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,777 associations by consensus.

Cardiac muscle cell action potential involved in contraction by ADGRL2 expression — STOMACH

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