ADGRG7

Across TCGA cell cohorts, ADGRG7 mutation is significantly associated with the RNA expression of many other genes, with 135 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADGRG7-associated genes across cancer lineages are UNCX, OR9K2, and CNGA2. Each is linked with ADGRG7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRG7-to-partner and partner-to-ADGRG7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UNCX grouped by ADGRG7-low versus ADGRG7-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG7→partner) and Y-score (partner→ADGRG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	UNCX →	+0.010	+4.087	<.001	.009	3	1
URINARY_TRACT	OR9K2 →	+0.015	+4.087	<.001	.009	3	1
URINARY_TRACT	CNGA2 →	+0.012	+5.044	<.001	<.001	3	1
BREAST	GFRA4 →	+0.022	+5.169	<.001	.005	3	1
LUNG_SCLC	KRTAP4-5 →	+0.047	+5.029	<.001	.006	3	1
LUNG_SCLC	OR6B1 →	+0.071	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 135 associations by consensus.

UNCX by ADGRG7 expression — URINARY_TRACT

Explore this box plot interactively →