ADGRG5

Across TCGA pan-cancer cohorts, ADGRG5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ADGRG5 data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ADGRG5 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ADGRG5 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, LSCC, and HNSC are the cancer types where ADGRG5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.904	0.370	.014	10	view →
LSCC	DFS	Median	II,III,IV	0.805	0.983	.042	3	view →
HNSC	DFS	Median	IV	1.000	0.486	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ADGRG5–LUAD (OS)

Open the LUAD breakdown →