ADGRG5

Across TCGA patient cohorts, ADGRG5 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,442 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADGRG5-associated proteins across cancer lineages are DEF6, GBP5, and LCP2. Each is linked with ADGRG5 in more than 7 cancer types. Because this analysis shows association rather than direction, both ADGRG5-to-partner and partner-to-ADGRG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRG5 versus DEF6 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG5→partner) and Y-score (partner→ADGRG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DEF6 →	+0.421	+0.535	<.001	<.001	3	8
BRCA	GBP5 →	+0.995	+0.734	<.001	<.001	3	8
HNSC	LCP2 →	+0.577	+0.785	<.001	<.001	3	8
OV	APOL3 →	+0.771	+0.693	<.001	<.001	3	8
LSCC	WAS →	+0.532	+0.913	<.001	<.001	3	7
BRCA	ZAP70 →	+0.784	+0.823	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,442 associations by consensus.

ADGRG5 vs DEF6 — OV

Explore this scatter interactively →