ADGRG5

Across TCGA patient cohorts, ADGRG5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,312 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADGRG5-associated genes across cancer lineages are CD69, STAT4, and GPR183. Each is linked with ADGRG5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADGRG5-to-partner and partner-to-ADGRG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRG5 versus CD69 in CCRCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG5→partner) and Y-score (partner→ADGRG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CD69 →	+1.405	+1.238	.003	.007	3	3
LSCC	STAT4 →	+0.870	+0.741	<.001	<.001	3	3
CCRCC	GPR183 →	+1.150	+1.364	<.001	.002	3	3
HNSC	HLA-DMA →	+0.803	+0.498	.005	.001	3	3
HNSC	TRAJ33 →	+1.300	+0.482	.005	.001	3	3
LSCC	SMAP2 →	+0.763	+0.719	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,312 associations by consensus.

ADGRG5 vs CD69 — CCRCC

Explore this scatter interactively →