ADGRG5

Across TCGA cell cohorts, ADGRG5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,874 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADGRG5-associated GO terms across cancer lineages are Body fluid secretion, Cellular response to alcohol, and Protein localization to cytoplasmic stress granule. Each is linked with ADGRG5 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADGRG5-to-partner and partner-to-ADGRG5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Body fluid secretion grouped by ADGRG5-low versus ADGRG5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG5→partner) and Y-score (partner→ADGRG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Body fluid secretion →	+0.130	+1.253	.001	.001	3	7
BLOOD_Lymphoma	Cellular response to alcohol →	+0.062	+2.152	<.001	<.001	3	5
BLOOD_Leukemia	Protein localization to cytoplasmic stress granule →	+0.072	+1.544	<.001	<.001	3	5
OESOPHAGUS	Semaphorin-plexin signaling pathway →	+0.108	+0.951	<.001	<.001	3	5
LUNG_SCLC	Negative regulation of T cell mediated cytotoxicity →	+0.656	+1.576	.005	.003	3	5
LARGE_INTESTINE	Fatty acid transmembrane transport →	+0.084	+0.987	.003	.005	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,874 associations by consensus.

Body fluid secretion by ADGRG5 expression — STOMACH

Explore this box plot interactively →