Across TCGA patient cohorts, ADGRG3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,570 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ADGRG3-associated genes across cancer lineages are CXCR1, MEFV, and AQP9. Each is linked with ADGRG3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADGRG3-to-partner and partner-to-ADGRG3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG3→partner) and Y-score (partner→ADGRG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CXCR1 →	+1.864	+1.646	<.001	<.001	3	5
PDAC	MEFV →	+1.091	+1.298	<.001	<.001	3	4
PDAC	AQP9 →	+2.099	+1.377	<.001	<.001	3	4
GBM	PLAUR →	+1.316	+1.227	.004	<.001	3	4
GBM	SRGN →	+1.352	+1.098	<.001	.004	3	4
GBM	G0S2 →	+1.980	+1.223	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,570 associations by consensus.

Exploration

ADGRG3 survival (RNA) · tumor vs normal (RNA) · all ADGRG3 data types