Across TCGA patient cohorts, ADGRG3 mutation is significantly associated with the RNA expression of many other genes, with 2,606 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ADGRG3-associated genes across cancer lineages are TRGV3, KCTD9, and ANP32B. Each is linked with ADGRG3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADGRG3-to-partner and partner-to-ADGRG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG3→partner) and Y-score (partner→ADGRG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRGV3 →	+0.631	+3.778	<.001	.001	3	3
SKCM	KCTD9 →	+0.585	+2.597	.005	.005	3	3
SKCM	ANP32B →	+0.402	+2.826	.004	.001	3	3
SKCM	MSANTD3 →	+0.559	+3.916	.001	<.001	3	3
SKCM	UFD1 →	+0.347	+1.970	.001	.002	3	3
SKCM	UBE2L3 →	+0.288	+2.471	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,606 associations by consensus.

Exploration

ADGRG3 survival (RNA) · tumor vs normal (RNA) · all ADGRG3 data types