Across TCGA cell cohorts, ADGRG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,317 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADGRG3-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Protein exit from endoplasmic reticulum. Each is linked with ADGRG3 in more than 9 cancer types. Because this analysis shows association rather than direction, both ADGRG3-to-partner and partner-to-ADGRG3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG3→partner) and Y-score (partner→ADGRG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.045	+0.092	.007	.005	3	10
BLOOD_Myeloma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.060	+0.046	.009	.003	2	8
STOMACH	Protein exit from endoplasmic reticulum →	+0.103	+0.331	<.001	.008	3	7
BLOOD_Leukemia	Response to topologically incorrect protein →	+0.039	+1.199	.001	.008	2	7
OVARY	Cellular response to topologically incorrect protein →	+0.062	+0.086	.001	.004	2	7
BLOOD_Myeloma	Negative regulation of endoplasmic reticulum unfolded protein response →	+0.094	+0.033	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,317 associations by consensus.

Exploration

ADGRG3 survival (RNA) · tumor vs normal (RNA) · all ADGRG3 data types