Across TCGA cell cohorts, ADGRG3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADGRG3-associated genes across cancer lineages are OBP2A, TRIM51, and GJD2. Each is linked with ADGRG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRG3-to-partner and partner-to-ADGRG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG3→partner) and Y-score (partner→ADGRG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OBP2A →	+0.094	+2.878	<.001	.009	3	1
LARGE_INTESTINE	TRIM51 →	+0.030	+3.115	.001	.004	3	1
LARGE_INTESTINE	GJD2 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	CRYBA4 →	+0.580	+3.626	<.001	.003	3	1
LARGE_INTESTINE	USP17L7 →	+0.059	+3.333	<.001	.009	3	1
LARGE_INTESTINE	SMIM33 →	+0.691	+3.426	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

ADGRG3 survival (RNA) · tumor vs normal (RNA) · all ADGRG3 data types