Across TCGA patient cohorts, ADGRG1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,737 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADGRG1-associated genes across cancer lineages are CMTM4, CSF2RB, and CYTIP. Each is linked with ADGRG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADGRG1-to-partner and partner-to-ADGRG1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG1→partner) and Y-score (partner→ADGRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CMTM4 →	+0.973	+0.603	<.001	<.001	3	6
BRCA	CSF2RB →	-0.906	-0.316	.003	.005	3	6
HNSC	CYTIP →	-0.801	-0.405	.001	<.001	3	5
BRCA	IL2RB →	-0.933	-0.500	<.001	<.001	3	5
HNSC	TLR8 →	-0.937	-0.539	<.001	<.001	3	5
HNSC	PLEK →	-1.188	-0.645	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,737 associations by consensus.

Exploration

ADGRG1 survival (RNA) · tumor vs normal (RNA) · all ADGRG1 data types