Across TCGA cell cohorts, ADGRG1 mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADGRG1-associated genes across cancer lineages are LRIT1, OR10W1, and FAM205A. Each is linked with ADGRG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRG1-to-partner and partner-to-ADGRG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG1→partner) and Y-score (partner→ADGRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LRIT1 →	+0.023	+3.269	<.001	.007	3	2
LARGE_INTESTINE	OR10W1 →	+0.008	+3.240	.001	.004	3	1
LARGE_INTESTINE	FAM205A →	+0.018	+4.252	<.001	<.001	3	1
SKIN	H2BW2 →	+0.087	+4.467	<.001	.004	3	1
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	1
CNS	KLHL1 →	+0.021	+3.774	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

ADGRG1 survival (RNA) · tumor vs normal (RNA) · all ADGRG1 data types