ADGRF5

Across TCGA patient cohorts, ADGRF5 protein abundance is significantly associated with the RNA expression of many other genes, with 19,842 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADGRF5-associated genes across cancer lineages are PCDH12, CD93, and KDR. Each is linked with ADGRF5 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADGRF5-to-partner and partner-to-ADGRF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRF5 versus PCDH12 in CCRCC, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF5→partner) and Y-score (partner→ADGRF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PCDH12 →	+1.124	+0.579	<.001	<.001	3	7
CCRCC	CD93 →	+0.905	+0.560	<.001	<.001	3	7
CCRCC	KDR →	+1.238	+0.514	<.001	<.001	3	7
CCRCC	ESAM →	+1.044	+0.572	<.001	<.001	3	7
CCRCC	ADGRL4 →	+1.027	+0.516	<.001	<.001	3	7
OV	FLT1 →	+1.005	+0.632	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,842 associations by consensus.

ADGRF5 vs PCDH12 — CCRCC

Explore this scatter interactively →