ADGRF5

Across TCGA cell cohorts, ADGRF5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,805 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ADGRF5-associated GO terms across cancer lineages are Negative regulation of mRNA metabolic process, mRNA transcription, and Regulation of alternative mRNA splicing, via spliceosome. Each is linked with ADGRF5 in more than 7 cancer types. Because this analysis shows association rather than direction, both ADGRF5-to-partner and partner-to-ADGRF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA metabolic process grouped by ADGRF5-low versus ADGRF5-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF5→partner) and Y-score (partner→ADGRF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of mRNA metabolic process →	+0.033	+2.040	.005	.003	3	7
OESOPHAGUS	mRNA transcription →	+0.062	+0.279	<.001	.002	3	7
SOFT_TISSUE	Regulation of alternative mRNA splicing, via spliceosome →	+0.109	+1.027	<.001	.008	1	8
STOMACH	Positive regulation of protein localization to nucleus →	+0.100	+0.308	<.001	.002	3	6
OESOPHAGUS	Regulation of stress-activated MAPK cascade →	+0.096	+0.265	<.001	.004	3	6
BLOOD_Lymphoma	Protein localization to lipid droplet →	+0.071	+0.040	.007	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,805 associations by consensus.

Negative regulation of mRNA metabolic process by ADGRF5 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →