ADGRF3

Across TCGA patient cohorts, ADGRF3 mutation is significantly associated with the RNA expression of many other genes, with 2,791 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADGRF3-associated genes across cancer lineages are MIR6893, PANK4, and CHAF1A. Each is linked with ADGRF3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADGRF3-to-partner and partner-to-ADGRF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6893 grouped by ADGRF3-low versus ADGRF3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF3→partner) and Y-score (partner→ADGRF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR6893 →	+0.417	+2.611	.001	.004	3	3
UCEC	PANK4 →	+0.326	+2.468	.001	.001	3	3
UCEC	CHAF1A →	+0.550	+2.213	<.001	.001	3	3
UCEC	RRM2 →	+0.686	+2.108	<.001	.002	3	3
LUSC	MIR4296 →	+0.659	+4.578	<.001	.001	3	3
UCEC	BBS4 →	+0.456	+2.831	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,791 associations by consensus.

MIR6893 by ADGRF3 expression — COAD

Explore this box plot interactively →