ADGRF3

Across TCGA cell cohorts, ADGRF3 mutation is significantly associated with the RNA expression of many other genes, with 1,388 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADGRF3-associated genes across cancer lineages are OR1L6, C2orf80, and TNP1. Each is linked with ADGRF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRF3-to-partner and partner-to-ADGRF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L6 grouped by ADGRF3-low versus ADGRF3-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF3→partner) and Y-score (partner→ADGRF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	OR1L6 →	+0.020	+5.169	<.001	.004	3	2
BONE	C2orf80 →	+0.126	+5.169	<.001	.004	3	1
SOFT_TISSUE	TNP1 →	+1.110	+4.369	<.001	.008	3	1
SOFT_TISSUE	C8orf74 →	+0.022	+4.369	<.001	.008	3	1
SOFT_TISSUE	RLN3 →	+0.030	+4.369	<.001	.008	3	1
LARGE_INTESTINE	PES1 →	+0.507	+3.916	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,388 associations by consensus.

OR1L6 by ADGRF3 expression — BONE

Explore this box plot interactively →