ADGRF2

Across TCGA patient cohorts, ADGRF2 mutation is significantly associated with the RNA expression of many other genes, with 2,911 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADGRF2-associated genes across cancer lineages are RN7SKP169, PSAT1P4, and RNA5SP534. Each is linked with ADGRF2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADGRF2-to-partner and partner-to-ADGRF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP169 grouped by ADGRF2-low versus ADGRF2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF2→partner) and Y-score (partner→ADGRF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP169 →	+0.118	+4.070	.007	.009	3	3
CESC	PSAT1P4 →	+0.131	+4.503	<.001	.005	3	3
LUSC	RNA5SP534 →	+0.335	+3.706	<.001	.003	3	3
COAD	RPS17P1 →	+1.115	+3.468	<.001	.008	3	2
COAD	RPS23P9 →	+0.158	+3.374	<.001	.008	3	2
COAD	FABP5P11 →	+0.609	+3.773	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,911 associations by consensus.

RN7SKP169 by ADGRF2 expression — COAD

Explore this box plot interactively →