ADGRF2

Across TCGA cell cohorts, ADGRF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 706 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ADGRF2-associated GO terms across cancer lineages are Cell-matrix adhesion, Cell-substrate junction assembly, and Cell-substrate junction organization. Each is linked with ADGRF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADGRF2-to-partner and partner-to-ADGRF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-matrix adhesion grouped by ADGRF2-low versus ADGRF2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF2→partner) and Y-score (partner→ADGRF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cell-matrix adhesion →	+0.079	+0.094	.002	.007	3	5
LUNG_NSCLC_LUAD	Cell-substrate junction assembly →	+0.138	+0.103	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Cell-substrate junction organization →	+0.119	+0.092	<.001	.003	3	5
LUNG_NSCLC_LUAD	Bundle of His cell to Purkinje myocyte communication →	+0.228	+0.087	.003	.003	3	5
UPPER_AERODIGESTIVE_TRACT	B cell apoptotic process →	+0.170	+0.117	<.001	.007	2	6
UPPER_AERODIGESTIVE_TRACT	Skin development →	+0.156	+0.182	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 706 associations by consensus.

Cell-matrix adhesion by ADGRF2 expression — PANCREAS

Explore this box plot interactively →