ADGRE4P

Across TCGA patient cohorts, ADGRE4P mutation is significantly associated with the RNA expression of many other genes, with 528 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADGRE4P-associated genes across cancer lineages are RPS4Y2, RNU6-11P, and GJE1. Each is linked with ADGRE4P in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRE4P-to-partner and partner-to-ADGRE4P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS4Y2 grouped by ADGRE4P-low versus ADGRE4P-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRE4P→partner) and Y-score (partner→ADGRE4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPS4Y2 →	+0.035	+3.551	<.001	.005	3	2
SKCM	RNU6-11P →	+0.194	+2.210	<.001	.005	3	2
CESC	GJE1 →	+0.041	+5.060	<.001	.001	3	2
CESC	NME1P1 →	+0.112	+4.669	<.001	.007	3	2
UCEC	AAGAB →	+0.522	+2.265	.001	.006	3	2
SKCM	PDE10A →	+0.576	+3.594	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 528 associations by consensus.

RPS4Y2 by ADGRE4P expression — BRCA

Explore this box plot interactively →