ADGRE4P

Across TCGA patient cohorts, ADGRE4P mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADGRE4P-associated genes across cancer lineages are ACC1, NDRG1_pT346, and TFRC. Each is linked with ADGRE4P in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRE4P-to-partner and partner-to-ADGRE4P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by ADGRE4P-low versus ADGRE4P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRE4P→partner) and Y-score (partner→ADGRE4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.339	+2.000	.038	.032	3	2
UCEC	NDRG1_pT346 →	-0.526	-3.321	.017	.010	3	2
UCEC	TFRC →	+0.479	+3.000	.045	.036	3	2
UCEC	Caspase-8 →	-0.283	-2.558	.012	.010	3	2
UCEC	EGFR_pY1068 →	-0.335	-2.459	.003	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.169	-1.986	.026	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

ACC1 by ADGRE4P expression — UCEC

Explore this box plot interactively →