ADGRE3

Across TCGA patient cohorts, ADGRE3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,548 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ADGRE3-associated genes across cancer lineages are AQP9, CXCL5, and LINC01506. Each is linked with ADGRE3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADGRE3-to-partner and partner-to-ADGRE3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRE3 versus AQP9 in BRCA, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRE3→partner) and Y-score (partner→ADGRE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AQP9 →	+2.354	+1.514	<.001	.003	3	4
BRCA	CXCL5 →	+2.440	+2.140	.001	.004	3	4
BRCA	LINC01506 →	+0.938	+1.790	<.001	<.001	3	4
PDAC	MTCO3P23 →	+1.137	+2.412	.005	.004	3	3
HNSC	CSF3 →	+1.800	+1.212	<.001	.002	3	3
HNSC	CMTM2 →	+1.238	+1.624	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,548 associations by consensus.

ADGRE3 vs AQP9 — BRCA

Explore this scatter interactively →