ADGRD2

Across TCGA patient cohorts, ADGRD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,082 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ADGRD2-associated GO terms across cancer lineages are Protein insertion into mitochondrial inner membrane, Transcription elongation-coupled chromatin remodeling, and Positive regulation of telomerase RNA localization to Cajal body. Each is linked with ADGRD2 in more than 17 cancer types. Because this analysis shows association rather than direction, both ADGRD2-to-partner and partner-to-ADGRD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into mitochondrial inner membrane grouped by ADGRD2-low versus ADGRD2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRD2→partner) and Y-score (partner→ADGRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein insertion into mitochondrial inner membrane →	+0.102	+0.147	<.001	<.001	3	17
SCLC	Transcription elongation-coupled chromatin remodeling →	+0.129	+1.554	<.001	<.001	3	16
SCLC	Positive regulation of telomerase RNA localization to Cajal body →	+0.149	+1.283	.005	<.001	1	18
STAD	Microtubule polymerization or depolymerization →	+0.091	+0.169	<.001	<.001	3	16
STAD	Regulation of DNA binding →	+0.087	+0.164	<.001	<.001	3	16
STAD	Base-excision repair →	+0.098	+0.170	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,082 associations by consensus.

Protein insertion into mitochondrial inner membrane by ADGRD2 expression — STAD

Explore this box plot interactively →