ADGRD2

Across TCGA cell cohorts, ADGRD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,732 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ADGRD2-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with ADGRD2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ADGRD2-to-partner and partner-to-ADGRD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by ADGRD2-low versus ADGRD2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRD2→partner) and Y-score (partner→ADGRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of myoblast fusion →	+0.127	+0.326	<.001	.002	3	10
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.144	+0.299	<.001	.003	3	10
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.125	+0.324	<.001	.002	3	9
STOMACH	Negative regulation of myoblast fusion →	+0.147	+0.306	<.001	.003	3	9
STOMACH	Cytoplasmic translation →	+0.100	+0.305	<.001	.003	3	8
STOMACH	Regulation of DNA-templated transcription elongation →	+0.077	+0.315	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,732 associations by consensus.

Regulation of myoblast fusion by ADGRD2 expression — STOMACH

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