ADGRD1

Across TCGA cell cohorts, ADGRD1 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADGRD1-associated genes across cancer lineages are KRTAP10-4, OR10K2, and OR10T2. Each is linked with ADGRD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRD1-to-partner and partner-to-ADGRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-4 grouped by ADGRD1-low versus ADGRD1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRD1→partner) and Y-score (partner→ADGRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	KRTAP10-4 →	+0.029	+5.321	<.001	.005	3	1
BREAST	OR10K2 →	+0.047	+4.781	<.001	.003	3	1
BREAST	OR10T2 →	+0.137	+4.781	<.001	.003	3	1
BLOOD_Lymphoma	SEMG2 →	+0.023	+4.321	<.001	.002	3	1
STOMACH	HOXB1 →	+0.264	+3.632	.003	.009	3	1
STOMACH	SLC10A2 →	+1.034	+3.637	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

KRTAP10-4 by ADGRD1 expression — CNS

Explore this box plot interactively →