ADGRD1

Across TCGA cell cohorts, ADGRD1 mutation is significantly associated with the mutation status of many other genes, with 3,215 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADGRD1-associated genes across cancer lineages are ASIC3, DLGAP1, and IGSF9. Each is linked with ADGRD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADGRD1-to-partner and partner-to-ADGRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASIC3 grouped by ADGRD1-low versus ADGRD1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRD1→partner) and Y-score (partner→ADGRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	ASIC3 →	+3.857	+4.807	.002	.002	1	5
BLOOD_Leukemia	DLGAP1 →	+3.662	+3.820	<.001	<.001	1	4
BLOOD_Lymphoma	IGSF9 →	+3.232	+3.523	.006	.006	1	4
CNS	TDRD6 →	+6.044	+6.044	.001	.001	1	4
BREAST	DDX60L →	+3.442	+4.558	.003	.003	1	4
BREAST	ZNF467 →	+4.857	+4.297	.009	.009	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,215 associations by consensus.

ASIC3 by ADGRD1 expression — BREAST

Explore this box plot interactively →