ADGRB2

Across TCGA patient cohorts, ADGRB2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,482 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADGRB2-associated genes across cancer lineages are PRODH, LGALS1, and SOX10. Each is linked with ADGRB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRB2-to-partner and partner-to-ADGRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRB2 versus PRODH in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRB2→partner) and Y-score (partner→ADGRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.627	+0.335	.002	<.001	3	1
GBM	LGALS1 →	-0.575	-0.311	.006	.002	3	1
GBM	SOX10 →	+1.158	+0.261	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.034	+0.374	<.001	<.001	3	1
GBM	KDELR3 →	-0.350	-0.234	.003	.002	3	1
GBM	NEFH →	+1.107	+0.363	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,482 associations by consensus.

ADGRB2 vs PRODH — GBM

Explore this scatter interactively →