Across TCGA patient cohorts, ADGRA1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,832 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADGRA1-associated genes across cancer lineages are SNRPD3, PRODH, and SEZ6L. Each is linked with ADGRA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRA1-to-partner and partner-to-ADGRA1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRA1→partner) and Y-score (partner→ADGRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.359	+0.493	<.001	<.001	3	1
GBM	PRODH →	+0.746	+0.418	<.001	<.001	3	1
GBM	SEZ6L →	+1.177	+0.355	.001	<.001	3	1
GBM	SNU13 →	+0.276	+0.412	.003	.002	3	1
GBM	SEPTIN3 →	+1.051	+0.506	<.001	<.001	3	1
GBM	NEFH →	+1.008	+0.474	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,832 associations by consensus.

Exploration

ADGRA1 survival (RNA) · tumor vs normal (RNA) · all ADGRA1 data types