Across TCGA cell cohorts, ADGRA1 mutation is significantly associated with the RNA expression of many other genes, with 270 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADGRA1-associated genes across cancer lineages are SERPINA7, MS4A2, and C8orf89. Each is linked with ADGRA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRA1-to-partner and partner-to-ADGRA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRA1→partner) and Y-score (partner→ADGRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SERPINA7 →	+0.006	+3.491	<.001	.002	3	2
OESOPHAGUS	MS4A2 →	+0.050	+4.857	<.001	<.001	3	1
OESOPHAGUS	C8orf89 →	+0.182	+4.017	<.001	.007	3	1
BLOOD_Myeloma	MMP26 →	+0.026	+4.807	<.001	.006	3	1
BLOOD_Myeloma	SALL3 →	+0.060	+4.807	<.001	.006	3	1
BLOOD_Myeloma	RBP3 →	+0.006	+4.807	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 270 associations by consensus.

Exploration

ADGRA1 survival (RNA) · tumor vs normal (RNA) · all ADGRA1 data types