ADGB

Across TCGA pan-cancer cohorts, ADGB Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ADGB data layer compared with 22 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher ADGB Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ADGB expression acts as an unfavorable survival marker, although some lineages such as UCEC and SCLC show a favorable association.

LUSC, UCEC, and KIRC are the cancer types where ADGB Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	II,III,IV	0.131	0.715	<.001	31	view →
UCEC	DFS	Median	II,III,IV	0.891	0.291	.001	30	view →
KIRC	OS	Median	All	0.167	0.655	.038	12	view →
ACC	OS	Median	All	0.165	0.632	.016	12	view →
SCLC	DFS	Median	II,III,IV	1.000	0.558	.029	5	view →
SKCM	DFS	Median	All	0.333	0.622	.031	4	view →
LIHC	OS	Median	All	0.571	0.780	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ADGB–LUSC (DFS)

Open the LUSC breakdown →