ADGB

Across TCGA patient cohorts, ADGB protein abundance is significantly associated with the RNA expression of many other genes, with 6,145 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ADGB-associated genes across cancer lineages are FOS, ATF3, and FOSB. Each is linked with ADGB in more than 5 cancer types. Because this analysis shows association rather than direction, both ADGB-to-partner and partner-to-ADGB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGB versus FOS in CCRCC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGB→partner) and Y-score (partner→ADGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FOS →	+1.452	+0.389	<.001	<.001	3	6
CCRCC	ATF3 →	+1.621	+0.460	<.001	<.001	3	5
CCRCC	FOSB →	+1.904	+0.403	<.001	<.001	3	5
CCRCC	EGR1 →	+1.200	+0.362	<.001	<.001	3	4
CCRCC	IER2 →	+0.876	+0.508	<.001	<.001	3	4
HNSC	NR4A1AS →	+1.180	+0.649	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,145 associations by consensus.

ADGB vs FOS — CCRCC

Explore this scatter interactively →