ADGB

Across TCGA cell cohorts, ADGB RNA expression is significantly associated with the go_rna of many other GO terms, with 639 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADGB-associated GO terms across cancer lineages are Negative regulation of proteolysis, Positive regulation of execution phase of apoptosis, and Response to fluoride. Each is linked with ADGB in more than 3 cancer types. Because this analysis shows association rather than direction, both ADGB-to-partner and partner-to-ADGB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of proteolysis grouped by ADGB-low versus ADGB-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGB→partner) and Y-score (partner→ADGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of proteolysis →	+0.070	+0.028	.002	.005	3	3
BLOOD_Leukemia	Positive regulation of execution phase of apoptosis →	+0.067	+0.057	<.001	<.001	3	3
BLOOD_Leukemia	Response to fluoride →	+0.077	+0.049	.004	.006	3	3
LARGE_INTESTINE	Positive regulation of intestinal cholesterol absorption →	+0.123	+0.127	.006	.005	2	4
PANCREAS	Response to heat →	+0.066	+0.021	<.001	.008	3	3
BLOOD_Leukemia	Mitochondrial electron transport, cytochrome c to oxygen →	+0.050	+0.052	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 639 associations by consensus.

Negative regulation of proteolysis by ADGB expression — KIDNEY

Explore this box plot interactively →