ADD3

Across TCGA patient cohorts, ADD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,918 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADD3-associated proteins across cancer lineages are ADD1, ADD3_S677, and ADD3_S442. Each is linked with ADD3 in more than 8 cancer types. Because this analysis shows association rather than direction, both ADD3-to-partner and partner-to-ADD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADD3 versus ADD1 in GBM, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADD3→partner) and Y-score (partner→ADD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ADD1 →	+0.496	+0.825	<.001	<.001	3	9
GBM	ADD3_S677 →	+0.636	+0.726	<.001	<.001	3	8
BRCA	ADD3_S442 →	+0.634	+0.917	<.001	.001	3	6
OV	ADD3_S461 →	+0.867	+0.617	.007	.002	3	6
GBM	SPTAN1 →	+0.375	+0.687	<.001	<.001	3	6
PDAC	XPNPEP1 →	+0.326	+0.471	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,918 associations by consensus.

ADD3 vs ADD1 — GBM

Explore this scatter interactively →