ADD2

Across TCGA patient cohorts, ADD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,885 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADD2-associated proteins across cancer lineages are ADD2_S592, ADD2_S697, and TJP3_S112. Each is linked with ADD2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ADD2-to-partner and partner-to-ADD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADD2 versus ADD2_S592 in LSCC, with a Pearson correlation of 0.90.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADD2→partner) and Y-score (partner→ADD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADD2_S592 →	+1.875	+2.464	<.001	<.001	3	8
LSCC	ADD2_S697 →	+1.047	+2.102	<.001	<.001	3	7
UCEC	TJP3_S112 →	-0.637	-0.972	<.001	<.001	3	6
LSCC	ADD2_S596 →	+1.204	+2.217	<.001	<.001	3	6
GBM	CEP170 →	+0.371	+1.158	<.001	<.001	3	6
GBM	NRF1 →	+0.476	+1.071	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,885 associations by consensus.

ADD2 vs ADD2_S592 — LSCC

Explore this scatter interactively →