ADD2

Across TCGA patient cohorts, ADD2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,569 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADD2-associated genes across cancer lineages are HBA2, HBA1, and FOSB. Each is linked with ADD2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADD2-to-partner and partner-to-ADD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADD2 versus HBA2 in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADD2→partner) and Y-score (partner→ADD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HBA2 →	+1.844	+0.729	<.001	<.001	3	7
GBM	HBA1 →	+1.356	+0.370	.001	.001	3	7
OV	FOSB →	+1.342	+0.351	.004	.005	3	5
GBM	ALAS2 →	+0.772	+0.406	.001	.001	3	5
CCRCC	PF4 →	+0.674	+0.763	.004	<.001	3	5
BRCA	HBB →	+2.033	+0.697	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,569 associations by consensus.

ADD2 vs HBA2 — OV

Explore this scatter interactively →