ADD2

Across TCGA cell cohorts, ADD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,558 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ADD2-associated GO terms across cancer lineages are Establishment of RNA localization, Regulation of protein localization to Cajal body, and Positive regulation of protein localization to Cajal body. Each is linked with ADD2 in more than 13 cancer types. Because this analysis shows association rather than direction, both ADD2-to-partner and partner-to-ADD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of RNA localization grouped by ADD2-low versus ADD2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADD2→partner) and Y-score (partner→ADD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Establishment of RNA localization →	+0.107	+1.724	<.001	<.001	3	14
OESOPHAGUS	Regulation of protein localization to Cajal body →	+0.119	+2.918	<.001	<.001	3	13
OESOPHAGUS	Positive regulation of protein localization to Cajal body →	+0.119	+2.918	<.001	<.001	3	13
OESOPHAGUS	Protein localization to nucleus →	+0.069	+2.748	<.001	<.001	3	13
BREAST	Transcription initiation at RNA polymerase II promoter →	+0.066	+1.693	<.001	.009	2	13
OESOPHAGUS	Nucleic acid transport →	+0.106	+2.512	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,558 associations by consensus.

Establishment of RNA localization by ADD2 expression — BREAST

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