ADD1

Across TCGA patient cohorts, ADD1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,034 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADD1-associated genes across cancer lineages are ADD3, PHYHIP, and CCNB1. Each is linked with ADD1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ADD1-to-partner and partner-to-ADD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADD1 versus ADD3 in BRCA, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADD1→partner) and Y-score (partner→ADD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ADD3 →	+1.389	+0.400	<.001	<.001	3	9
GBM	PHYHIP →	+1.566	+0.408	<.001	<.001	3	7
UCEC	CCNB1 →	-1.162	-0.310	<.001	<.001	3	7
BRCA	JAM2 →	+0.782	+0.330	<.001	<.001	3	7
GBM	NEGR1 →	+0.922	+0.261	<.001	<.001	3	7
GBM	PLCXD3 →	+0.832	+0.372	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,034 associations by consensus.

ADD1 vs ADD3 — BRCA

Explore this scatter interactively →