ADD1

Across TCGA cell cohorts, ADD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,539 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ADD1-associated GO terms across cancer lineages are Endosomal transport, Regulation of aggrephagy, and Golgi vesicle transport. Each is linked with ADD1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ADD1-to-partner and partner-to-ADD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by ADD1-low versus ADD1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADD1→partner) and Y-score (partner→ADD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.075	+1.007	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of aggrephagy →	+0.120	+0.654	<.001	.001	3	14
BREAST	Golgi vesicle transport →	+0.064	+0.730	<.001	<.001	3	14
STOMACH	Vacuole organization →	+0.065	+0.724	<.001	<.001	3	14
STOMACH	Macroautophagy →	+0.066	+0.777	.003	<.001	3	13
STOMACH	Retrograde transport, endosome to Golgi →	+0.072	+0.750	.005	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,539 associations by consensus.

Endosomal transport by ADD1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →