ADCYAP1R1

Across TCGA pan-cancer cohorts, ADCYAP1R1 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ADCYAP1R1 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher ADCYAP1R1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ADCYAP1R1 expression acts as an unfavorable survival marker.

STAD, DLBC, and LGG are the cancer types where ADCYAP1R1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.001	0.667	<.001	27	view →
DLBC	OS	Median	II,III,IV	0.118	0.802	.025	12	view →
LGG	OS	Median	All	0.208	0.896	<.001	12	view →
UCEC	OS	Median	IV	0.225	0.772	<.001	12	view →
LIHC	DFS	Median	All	0.128	0.555	.024	6	view →
HNSC	DFS	Median	III,IV	0.101	0.680	<.001	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ADCYAP1R1–STAD (OS)

Open the STAD breakdown →