ADCY7

Across TCGA patient cohorts, ADCY7 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,038 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADCY7-associated proteins across cancer lineages are TRIM21, MYO1G, and PTPN6. Each is linked with ADCY7 in more than 7 cancer types. Because this analysis shows association rather than direction, both ADCY7-to-partner and partner-to-ADCY7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADCY7 versus TRIM21 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY7→partner) and Y-score (partner→ADCY7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM21 →	+0.419	+0.755	<.001	<.001	3	8
GBM	MYO1G →	+0.662	+0.676	<.001	<.001	3	7
GBM	PTPN6 →	+0.728	+0.754	<.001	<.001	3	7
GBM	SAMHD1 →	+0.472	+0.734	<.001	<.001	3	7
BRCA	COTL1 →	+0.635	+1.061	<.001	<.001	3	7
GBM	ALOX5 →	+0.803	+0.758	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,038 associations by consensus.

ADCY7 vs TRIM21 — GBM

Explore this scatter interactively →