ADCY7

Across TCGA patient cohorts, ADCY7 protein abundance is significantly associated with the RNA expression of many other genes, with 9,844 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADCY7-associated genes across cancer lineages are TMEM145, GAPT, and HCLS1. Each is linked with ADCY7 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADCY7-to-partner and partner-to-ADCY7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADCY7 versus TMEM145 in GBM, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY7→partner) and Y-score (partner→ADCY7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TMEM145 →	-0.741	-0.318	<.001	.001	3	4
OV	GAPT →	+1.080	+0.620	<.001	<.001	3	4
UCEC	HCLS1 →	+1.105	+0.468	<.001	.004	3	4
UCEC	MIR223HG →	+1.157	+0.555	<.001	.001	3	4
HNSC	RPL12P11 →	-0.941	-0.635	.006	<.001	3	4
GBM	LYL1 →	+0.637	+0.417	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,844 associations by consensus.

ADCY7 vs TMEM145 — GBM

Explore this scatter interactively →