ADCY6-DT

Across TCGA pan-cancer cohorts, ADCY6-DT RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated ADCY6-DT data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher ADCY6-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated ADCY6-DT expression acts as an unfavorable survival marker, although some lineages such as OV and BLCA show a favorable association.

OV, BLCA, and UVM are the cancer types where ADCY6-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	III,IV	0.385	0.272	<.001	84	view →
BLCA	DFS	Median	All	0.552	0.461	.007	52	view →
UVM	DFS	Tertile	All	0.766	0.428	.001	46	view →
ACC	OS	Quartile	All	0.289	0.907	.004	27	view →
KIRC	DFS	Quartile	IV	0.275	0.830	.012	20	view →
SKCM	DFS	Median	II,III,IV	0.639	0.468	.002	19	view →
THCA	DFS	Median	All	0.893	0.784	.012	19	view →
TGCT	DFS	Tertile	All	0.526	0.931	<.001	18	view →
LIHC	DFS	Quartile	All	0.305	0.583	.004	17	view →
UCS	DFS	Median	II,III,IV	0.591	0.304	.017	16	view →
PRAD	DFS	Tertile	All	0.683	0.858	.005	16	view →
ESCA	OS	Quartile	All	0.375	1.000	.009	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

ADCY6-DT–OV (OS)

Open the OV breakdown →