ADCY2

Across TCGA patient cohorts, ADCY2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,081 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADCY2-associated genes across cancer lineages are LINC01943, APOC1, and PGGT1BP1. Each is linked with ADCY2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADCY2-to-partner and partner-to-ADCY2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADCY2 versus LINC01943 in BRCA, with a Pearson correlation of -0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY2→partner) and Y-score (partner→ADCY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC01943 →	-1.640	-1.189	.006	.006	3	2
BRCA	APOC1 →	-3.144	-1.189	.009	.006	3	1
BRCA	PGGT1BP1 →	-0.525	-1.189	.004	.006	3	1
GBM	PRODH →	+0.774	+0.464	<.001	<.001	3	1
GBM	CRYBB3 →	+0.321	+0.370	.004	.004	3	1
GBM	GRK3 →	+0.389	+0.639	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,081 associations by consensus.

ADCY2 vs LINC01943 — BRCA

Explore this scatter interactively →