ADCY2

Across TCGA cell cohorts, ADCY2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,294 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ADCY2-associated GO terms across cancer lineages are Cytoplasmic translation, Response to potassium ion, and RNA splicing, via transesterification reactions. Each is linked with ADCY2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADCY2-to-partner and partner-to-ADCY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by ADCY2-low versus ADCY2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY2→partner) and Y-score (partner→ADCY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cytoplasmic translation →	+0.055	+0.720	<.001	.002	3	6
OESOPHAGUS	Response to potassium ion →	-0.214	-0.113	<.001	.006	3	5
SOFT_TISSUE	RNA splicing, via transesterification reactions →	+0.057	+0.751	<.001	.002	3	5
SOFT_TISSUE	Alternative mRNA splicing, via spliceosome →	+0.066	+0.769	<.001	<.001	3	5
LUNG_SCLC	RNA destabilization →	+0.055	+1.912	<.001	<.001	3	5
LUNG_SCLC	mRNA destabilization →	+0.056	+1.864	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,294 associations by consensus.

Cytoplasmic translation by ADCY2 expression — SOFT_TISSUE

Explore this box plot interactively →