ADCY10

Across TCGA patient cohorts, ADCY10 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,147 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ADCY10-associated GO terms across cancer lineages are DNA-templated transcription elongation, tRNA modification, and Positive regulation of double-strand break repair via homologous recombination. Each is linked with ADCY10 in more than 28 cancer types. Because this analysis shows association rather than direction, both ADCY10-to-partner and partner-to-ADCY10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription elongation grouped by ADCY10-low versus ADCY10-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY10→partner) and Y-score (partner→ADCY10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA-templated transcription elongation →	+0.079	+0.225	<.001	<.001	3	28
DLBC	tRNA modification →	+0.069	+0.140	.007	<.001	2	29
STAD	Positive regulation of double-strand break repair via homologous recombination →	+0.064	+0.206	<.001	<.001	3	27
ESCA	Positive regulation of DNA metabolic process →	+0.081	+0.387	<.001	<.001	2	28
STAD	Transcription initiation at RNA polymerase II promoter →	+0.070	+0.234	<.001	<.001	3	27
STAD	tRNA metabolic process →	+0.069	+0.228	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,147 associations by consensus.

DNA-templated transcription elongation by ADCY10 expression — STAD

Explore this box plot interactively →